Search on: WW DOMAINS 
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Descriptor English:   WW Domains 
Descriptor Spanish:   Dominios WW 
Descriptor Portuguese:   Domínios WW 
Synonyms English:   Domain, WW
Domains, WW
WW Domain  
Tree Number:   G02.111.570.820.709.275.750.500.937
Definition English:   An approximately 40 amino acid protein domain that occurs in a variety of unrelated proteins and may be repeated up to four times in some proteins. It is characterized by two TRYPTOPHAN residues (WW) about 20 amino acids apart and folds into a stable triple-stranded BETA-SHEET. It binds PROLINE-RICH PROTEIN DOMAINS and PHOSPHOSERINE or PHOSPHOTHREONINE-containing protein domains that occur in many signal-transducing and cytoskeletal proteins such as DYSTROPHIN. 
History Note English:   2018 
Allowable Qualifiers English:  
DE drug effects GE genetics
IM immunology PH physiology
RE radiation effects  
Record Number:   57257 
Unique Identifier:   D000074585 

Occurrence in VHL:
 

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